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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPR All Species: 36.36
Human Site: S35 Identified Species: 61.54
UniProt: P35270 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35270 NP_003115.1 261 28048 S35 A S L L S P G S V L V L S A R
Chimpanzee Pan troglodytes XP_525784 261 27897 S35 A S L L S P G S V L V L S A R
Rhesus Macaque Macaca mulatta XP_001103332 261 28016 S35 A S L L S P G S V L V L N A R
Dog Lupus familis XP_540234 267 28592 S41 A R L L A P G S V L V L S A R
Cat Felis silvestris
Mouse Mus musculus Q64105 261 27865 S36 A R L L S P G S V M L V S A R
Rat Rattus norvegicus P18297 262 28110 S36 A G L L S P G S V L L L S A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520473 236 25629 E29 G A C A E R M E G A Y A E G P
Chicken Gallus gallus Q8JIS3 246 26149 T37 C K A G A R V T A L S R T A A
Frog Xenopus laevis Q7ZY31 263 28687 S39 C P R V L P G S T L L L V S R
Zebra Danio Brachydanio rerio NP_001019601 261 28523 S37 A A R V S P G S V L V L A A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624245 354 39811 S128 G S I L E K G S H I L L L A T
Nematode Worm Caenorhab. elegans Q21929 251 27201 I37 A K A G A Q V I A F A R N E A
Sea Urchin Strong. purpuratus XP_783056 275 30198 S38 S A K F G P G S V L V L T G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40579 254 27462 V30 F S L D K D T V V Y G V A R S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 96.9 80.9 N.A. 74.3 74.4 N.A. 46.3 26.4 55.5 52.4 N.A. N.A. 25.4 26 39.6
Protein Similarity: 100 98 99.6 89.1 N.A. 86.5 88.1 N.A. 58.6 44.8 69.9 74.3 N.A. N.A. 41.5 46.3 58.5
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 86.6 N.A. 0 13.3 40 73.3 N.A. N.A. 40 6.6 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 33.3 60 93.3 N.A. N.A. 60 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 22 15 8 22 0 0 0 15 8 8 8 15 65 15 % A
% Cys: 15 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 15 0 0 8 0 0 0 0 8 8 0 % E
% Phe: 8 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 15 8 0 15 8 0 72 0 8 0 8 0 0 15 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % I
% Lys: 0 15 8 0 8 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 50 50 8 0 0 0 0 65 29 65 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % N
% Pro: 0 8 0 0 0 65 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 15 15 0 0 15 0 0 0 0 0 15 0 8 65 % R
% Ser: 8 36 0 0 43 0 0 72 0 0 8 0 36 8 8 % S
% Thr: 0 0 0 0 0 0 8 8 8 0 0 0 15 0 8 % T
% Val: 0 0 0 15 0 0 15 8 65 0 43 15 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _